For non-prescription products, read the label or package ingredients carefully. Some side effects can be serious. Active ingredients: Oxymetazoline hydrochloride 0.05%, Inactive ingredients: benzalkonium chloride solution, edetate disodium, polyethylene glycol, povidone, propylene glycol, purified water, sodium phosphate dibasic, sodium phosphate monobasic, Stop use and ask a doctor if symptoms persist. Intranasal use of oxymetazoline may occasionally cause systemic sympathomimetic effects such as hypertension, nervousness, nausea, dizziness, headache, insomnia, palpitation, or reflex bradycardia 7). Afrin (Oxymetazoline) may also be used for other conditions as determined by your doctor. For products that come in a pump dispenser, press down on the rim with a firm, even stroke and breathe in deeply. In these cases, your doctor may want to change the dose, or other precautions may be necessary. A case report of an abrupt withdrawal in a healthy man of oxymetazoline nasal spray precipitated a prolonged panic disorder that required hospitalization with extensive evaluations 9). Keep out of reach of children. Many medicines have not been tested in older people. If your dose is different, do not change it unless your doctor tells you to do so. For this medicine, the following should be considered: Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. This may increase the chance of side effects during treatment. (ed.). If you notice any other effects, check with your healthcare professional. Always read the full labeling before using any drug product. The amount of medicine that you take depends on the strength of the medicine. 2006., p. 2824, Baxi LV et al; J Obstet Gynecol 153 (Dec): 799 -800, 1985, Rayburn WF, et al; Obstet Gynecol 76 (2): 180-2, 1990, Anderson PO. If you are using a product that comes in a pump dispenser, press down on the rim several times before using your first dose to prime the pump, according to the directions on the label. If you experience any of these symptoms, call your doctor immediately: Oxymetazoline nasal spray may cause other side effects. A total of 307 patients with acute rhinitis entered a study to compare the difference between oxymetazoline with preservative and oxymetazoline without preservative. Lisinopril is an oral medication used to treat hypertension (high blood pressure) and heart failure. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. To spray, hold bottle with thumb at base and nozzle between first and second fingers. Children may be especially sensitive to the effects of oxymetazoline. Do not use more or less of it or use it more often than prescribed by your doctor or directed on the label. A patient prescribed oxymetazoline hydrochloride nasal drops presented with recurrent ventricular tachycardia of fascicular origin 13). Place tip of nozzle just past nasal opening (approximately 1/8″). To prevent the spread of infection, do not share your spray dispenser with anyone else. We comply with the HONcode standard for trustworthy health information -, Drug class: nasal antihistamines and decongestants. Sudafed (pseudoephedrine) Prescription or OTC; 82% of people say it’s worth it; 3 dosage forms There is only one standard dose of Afrin, regardless of your age or the severity of your congestion. CMAJ : Canadian Medical Association Journal. Learn about GoodRx Gold; 4; alternatives. The product's dosage form is spray and is administered via nasal form. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. When evaluated according to the parameters “feeling of dryness in nasal mucosa” and “burning sensation”, a 0.05% spray, which contains the active agent oxymetazoline without preservatives, proved to be considerably superior to preparations containing the preservative benzalkonium chloride 8). If you miss a dose of this medicine, take it as soon as possible. If you use Afrin (Oxymetazoline) nasal spray for more often or for longer than the recommended period of time, your congestion may get worse or may improve but come back. Severe hypertension with reflex bradycardia progressed to sinus arrest and was successfully treated with atropine and cardiopulmonary resuscitation 12). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC516194/, Fivhas GD, Newman NJ; Am J Ophthalmol 127 (1): 104-6, 1999 https://www.ncbi.nlm.nih.gov/pubmed/9933016, Magargal LE et al; Ann Ophthalmol 17 (8): 500-1,1985 https://www.ncbi.nlm.nih.gov/pubmed/2413795, Glazener F et al; N Engl J Med 309 (Sep 22): 731, 1983. Cardiac ultrasound showed a calcified lesion, presumably a fibroma arising from the interventricular septum. do not use for more than 3 days. Before using the first time, prime metered pump by depressing pump firmly several times. Elderly: There is no need for dosage reduction in the elderly for nasal administration. Medically reviewed by Drugs.com. Relevant published information was not found. Facilitates intranasal exam or before nasal surgery. Generic Name: oxymetazoline (ox-i-me-TAZ-oh-leen) (Nasal route). Dosage Guidelines & Tips How to take Afrin Saline(Nasal)? The following information includes only the average doses of this medicine. Out of scope information includes radiopharmaceuticals, contrast media, herbals, homeopathics, and food. Although no information exists on the use of Afrin (Oxymetazoline) specifically during breastfeeding, very little should reach the infant through breastmilk because of the local administration and limited absorption into the maternal bloodstream 5). Afrin (oxymetazoline) Prescription or OTC; 71% of people say it’s worth it; 1 dosage forms $5.1 is the lowest price near you; Want to save even more money? Maternal Drug Levels. If needed, blow the nose gently again and repeat the spray process until the total dose is used. Afrin (Oxymetazoline) nasal spray should not be used to treat children younger than 6 years of age unless it is recommended by a doctor. Oxymetazoline is used for the temporary relief of nasal (of the nose) congestion or stuffiness caused by hay fever or other allergies, colds, or sinus trouble. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. A repeat angiogram at 6 weeks showed complete resolution of most areas of arterial narrowing 17). Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Medscape - Pruritis, sedation, anxiety-specific dosing forVistaril (hydroxyzine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & … Make sure you tell your doctor if you have any other medical problems, especially: Afrin (Oxymetazoline) nasal spray comes as a solution (liquid) to spray into your nose. Follow your doctor's orders or the directions on the label. Not to exceed 2 doses/24 hr for 3-5 days. Use only as directed. Thunderclap headache and reversible segmental cerebral vasoconstriction associated with use of oxymetazoline nasal spray. It is recommended over oral systemic decongestants such as pseudoephedrine during breastfeeding 6). Use Afrin (Oxymetazoline) nasal spray exactly as directed. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Afrin is a drug which is used for the relief of nasal stuffiness and congestion, which can be caused by hay fever, cold or sinusitis. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Follow your doctor's orders or the directions on the label. This medicine may also be used for other conditions as determined by your doctor. temporarily relieves nasal congestion due to: temporarily relieves sinus congestion and pressure, shrinks swollen membranes so you can breathe more freely, trouble urinating due to an enlarged prostate gland. Hold white tabs, press grooved area of cap firmly and turn counter clockwise. How to use Afrin (Pseudoephedrine) Tablet, Extended Release. Medicare coverage and pricing details for Oxymetazoline. ; Children below 6 years of age: It is not suitable for children below 6 years of age. Oxymetazoline hydrochloride ophthalmic or nasal solutions should be used during pregnancy only when instructed by a clinician 1). Afrin (Oxymetazoline) is a selective α2A-adrenergic receptor agonist a sympathomimetic amine in a class of medications called nasal decongestants. Afrin Nasal spray is an over the counter medication used to treat nasal congestion. The amount of Afrin (Oxymetazoline) that you take depends on the strength of the medicine. Available for Android and iOS devices. •The recommended dosage is 2.5 mg/kg as an intravenous infusion over approximately 30 minutes once every 3 weeks. This may increase the chance of side effects during treatment. google_ad_client: "ca-pub-9759235379140764", When choosing an allergy treatment, don't settle for anything less than more complete allergy relief. Elderly: There is no need for dosage reduction in the elderly for nasal administration. Call your doctor if you have any unusual problems while using this medication. The following information includes only the average doses of this medicine. Afrin nasal spray is used for the temporary relief of nasal congestion associated with acute and chronic rhinitis or stuffiness caused by hay fever or other allergies and common colds. Rinse the tip of the dispenser with hot water or wipe it clean after you use it. These side effects may go away during treatment as your body adjusts to the medicine. Do not use for more than 3 days. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Be sure to tell your doctor or pharmacist if you are taking the following medications or have stopped taking them within the past two weeks: isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate). Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. If swallowed, get medical help or contact a Poison Control Center right away. Do not use more than two times in twenty four hours. Rinse the dropper with hot water and dry with a clean tissue. This web page has a list of dosage form terms and National Cancer Institute Thesaurus concept codes associated with those term for use in Structured Product Labeling (SPL) documents submitted to FDA. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. AFRIN NO DRIP ORIGINAL prescription and dosage sizes information for physicians and healthcare professionals. Oxymetazoline is a topical decongestant, used in the form of oxymetazoline hydrochloride.It was developed from xylometazoline at E. Merck Darmstadt by Fruhstorfer in 1961. If you become pregnant while using Afrin (Oxymetazoline) nasal spray, call your doctor. Afrin (Oxymetazoline) nasal spray is only for use in the nose. This medicine is available without a prescription. For Afrin (Oxymetazoline) nasal dosage form (pump mist or nasal spray): If you miss a dose of Afrin (Oxymetazoline), take it as soon as possible. Trouble urinating from an enlarged prostate—May make these conditions worse. Frequent or prolonged use may cause nasal congestion to recur or worsen. Do not use Afrin (Oxymetazoline) nasal spray for longer than 3 days. Adults and children 6 to under 12 years of age (with adult supervision): 2 or 3 sprays in each nostril not more often than every 10 to 12 hours. When you are taking Afrin (Oxymetazoline), it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Before using the first time, prime metered pump by. To do so may make your runny or stuffy nose worse and may increase the chance of side effects. Fully depress rim with a firm, even stroke and sniff deeply. Effects in Breastfed Infants: Relevant published information was not found. Call your doctor for medical advice about side effects. The dose of this medicine will be different for different patients. To avoid spreading a cold or infection, do not use the container for more than one person and throw the container away after your cold is better. Do not double doses. Afrin (Oxymetazoline) works by narrowing the blood vessels (vasoconstriction) in the nasal passages, thus decreasing nasal blood flow and nasal congestion. If pregnant or breast-feeding, ask a health professional before use. tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. 2000;16:294 https://www.ncbi.nlm.nih.gov/pubmed/11155604, Dorn M et al; HNO 51 (10): 794-9, 2003 https://www.ncbi.nlm.nih.gov/pubmed/14523532, Saadah HA; J Clin Psychiarty 48 (7): 293, 1987 https://www.ncbi.nlm.nih.gov/pubmed/3597333, Thrush DN; J Clin Anesth 7 (6): 5112-4; 1995 https://www.ncbi.nlm.nih.gov/pubmed/8534470, Khan A, Dewhurst N; Br J Clin Pract 51 (3): 192-3, 1997 https://www.ncbi.nlm.nih.gov/pubmed/9293069, Loewen AHS, Hudon ME, Hill MD. Keep from freezing. Push firmly down on cap and turn counter clockwise. Afrin(oxymetazoline): Symptomatic relief of nasal & nasopharyngeal congestion. Do not exceed 2 doses in any 24-hour period. There is no specific information about the use of Afrin (Oxymetazoline) in the elderly. ; Children below 6 years of age: It is not suitable for children below 6 years of age. Tilt the head back while standing or sitting up, or lie down on a bed and hang the head over the side. This product is available in the following dosage forms: It may not be specific to Afrin. If your dose is different, do not change it unless your doctor tells you to do so. Children up to 6 years of age—Use and dose must be determined by your doctor. Relevant published information was not found. The presence of other medical problems may affect the use of this medicine. Pharmacology, adverse reactions, warnings and side effects. Two weeks after discharge the headache had nearly resolved. Oxymetazoline nasal spray-Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days. headache, dizziness, drowsiness, or lightheadedness, Burning, dryness, or stinging inside of nose. Do not exceed 2 doses in any 24-hour period. American Hospital Formulary Service. Do not keep outdated medicine or medicine no longer needed. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Afrin (Oxymetazoline) nasal spray is usually used every 10 to 12 hours as needed, but not more often than twice in a 24-hour period. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Afrin is also used to relieve sinus congestion and pressure. The drug works for dogs and cats by stimulating receptors in blood vessels, leading to constriction (narrowing) of the small blood vessels within the nasal passages. Follow the directions on the package label or on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Blow your nose gently. There is no specific information about the use of oxymetazoline in the elderly. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. A case of chronic use of nasal oxymetazoline associated with thunderclap headache due to reversible segmental intracranial vasoconstriction is reported 15). Thunderclap headache is a hyperacute, severe headache that is so named because of its sudden onset. This medicine is available without a prescription. 0.05%. Infant Drug Levels. Other brands: Nostrilla, Mucinex Sinus-Max Full Force, Zicam Sinus Relief, Vicks Sinex Severe Nasal Spray, ... +18 more, epinephrine topical, sodium chloride nasal, pseudoephedrine, phenylephrine nasal, doxylamine. However, weigh the potential benefits against the potential risks before taking Afrin (Oxymetazoline) while breastfeeding. You should not use Afrin for more than three days. enable_page_level_ads: true The effects of repeated use of Afrin (Oxymetazoline) nasal spray in a 20-yr-old woman, with uncomplicated pregnancy, resulting in nonreactive nonstress test, late decelerations and fetal heart rate abnormalities, were reported. Firmly down on cap and turn counter clockwise a study to compare the between. And second fingers information includes only the average doses of this medicine, Oxymetazoline nasal spray that contains,! Significance and are not necessarily all-inclusive reflex bradycardia progressed to sinus arrest and successfully. 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