This procedure has been adapted from the microscale procedure described in the third edition of Macroscale and Microscale Organic Experiments by Kenneth L. Williamson (Houghton Mifflin, Boston, 1999). Start studying Experiment 11B: The Aldol Condensation. Add one mole equivalent amount of the ketone and 1 mL of 95 % ethanol to the vial and start stirring. In this experiment, a benzaldehyde derivative will be used as the carbonyl compound that contains no \(\alpha\)-protons, and acetophenone will act as the carbonyl compound containing \(\alpha\)-protons. CHEM 238 - 504 11.8.18 Experiment 9: The Aldol Condensation The objectives for this experiment were to use aldol condensation reactions to synthesis a colored cyclopenta-dienone, to use UV/VIS spectrophotometry to characterize the dienone, and finally to use computer visualization to better understand its unusual three-dimensional structure. The products are a series of analogs called benzalacetophenones, or chalcones. Learn vocabulary, terms, and more with flashcards, games, and other study tools. This procedure has been adapted from the microscale procedure described in the third edition of Macroscale and Microscale Organic Experiments by Kenneth L. Williamson (Houghton Mifflin, Boston, 1999). CHEM 322L Experiment 9: Aldol Reaction 1 9. CHEM 322: Crossed Aldol Condensation: Synthesis of Dibenzalacetone (1,5-Diphenyl-1,4-pentadien-3-one) Introduction: In this experiment, you will perform a type of base-catalyzed crossed aldol condensation called the Claisen-Schmidt reaction. The aldol reaction is … The recorded melting point was 84°C, which is close to cis, trans (Z,E) dibenzalacetone with melting point of 60°C. Start studying Exp. Aldol Reaction . Aldol Condensation Of Acetophenone With Anisaldehyde NaOH Cha, EtOH H MW = 136.15 G/mol MW= 120.15 G/mol MW=238.28 G/mol Trans-p-anisalacetophenone Procedure Into A 25 Or 50 ML Erlenmeyer Flask Are Placed 10 Mmole Of Acetophenone, 10 Mmole Of Anisaldehyde, 5 ML Of 95% Ethanol, And 8 ML Of 10% Sodium Hydroxide Solution. The reaction was monitored by TLC for one hour, and it was stopped at a little over half completion. Learn vocabulary, terms, and more with flashcards, games, and other study tools. 9: The Aldol Condensation. The purpose of this experiment was to carry out an aldol condensation to produce dibenzalacetone and determine which of the three possible isomers of dibenzalacetone (cis,cis, cis,trans, and trans,trans) is the major product. General Aldol Condensation Procedure. 9. Place ~ 1 mmol (weigh accurately) of the aldehyde into a conical vial equipped with a magnetic spin vane. Students worked individually on this experiment … M. Jones: Condensation Reactions, Aldol reaction, Chapter 17, Section 3, pgs 840-850. Experiment 19 — Aldol Condensation _____ Pre-lab preparation. CHEM 322L Experiment 9: Aldol Reaction 1 . Question: Experiment 9. ... Synthesis of 4-methoxychalcone utilized an Aldol condensation mechanism. Back to top; 13: Exp. (1) Write the mechanism of the base-catalyzed aldol condensation of acetone and a generalized aromatic aldehyde, Ar–CH=O to give the α,β-unsaturated product (i.e. The purpose of this experiment was to synthesize and purify 4-methoxychalcone via an Aldol condensation mechanism. Aldol Reaction M. Jones: Condensation Reactions, Aldol reaction, Chapter 17, Section 3, pgs 840-850. the reaction at the top of the … The product was then . The crude product Experiment 6 - Aldol Condensation Objective To provide experience with Aldol condensation, a useful reaction to prepare conjugated carbonyl systems. 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