To do so may increase the chance of side effects. My husband started on sulfasalazine a week ago on two a day. However, many people have no side effects or only have minor side effects. Sulfasalazine may cause blood problems. You will need frequent blood and urine checks. What are some other side effects of Sulfasalazine Tablets? Stomach pain or heartburn. The most common side effects are nausea or abdominal discomfort. Try not to let more than 8 … Sulfasalazine causes temporary infertility in males. These negative effects might evaporate as the body gets used to the medication. Fertility returns when the medicine is stopped. Sulfasalazine may cause side effects. It can also cause your urine or skin to turn yellowish-orange; this effect is harmless. Keep out of the sun. Sulfasalazine is given by mouth and is used off label to treat inflammatory large bowel disease and vasculitis. I hope it settles down for you and works well for your RA. Sulfasalazine Side Effects. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. What should I watch for? Sulfasalazine is associated with few common side effects. But I think it must be - after all, side effects are only known by getting feedback from the people using the drug. Dental work should be delayed until your blood counts have returned to normal. It is best to take this medicine right after meals, at evenly spaced times throughout the day and night. He has decided to stay on the same dose rather than increase it to see if it stabilises. Visit your doctor or health care professional for regular checks on your progress. He was fine for a few days but now has stomach pains and diarrhoea and is really feeling the cold. He's tried a couple of other tablets but had to stop those due to side effects such as blisters etc. In rheumatoid arthritis, the effect of sulfasalazine delayed release tablets can be assessed by the degree of improvement in the number and extent of actively inflamed joints. Side Effects What are the side effects of Sulfasalazine (Azulfidine)?. Oh, my GP said the itching wasnt a side effect of sulfazal. Some side effects that are sulfasalazine might not require any medical attention. This medicine can make you more sensitive to the sun. The Sulphasalazine is a DMARD and this can effect the white blood cells, sometimes they will withdraw the Dmard and try another one. Abdominal issues seem to resolve over time, especially when the drug is given at a low dose initially. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Headache. These problems may result in a greater chance of certain infections, slow healing, and bleeding of the gums. Give as directed by your veterinarian. The contraindications are textbook I understand , although I am not a GP or specialist. Certainly it went away when i stopped taking it. and the drug was replaced after a … Therefore, you should be careful when using regular toothbrushes, dental floss, and toothpicks. !!! xx Possible Side Effects. Side effects include dry eye, decreased appetite, vomiting, yellowing of the skin, eyes, or body fluids. When taking Sulfasalazine, reported side effects are usually mild and improve in time. I had this problem about twenty years ago. All drugs may cause side effects. 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