3.0 responsibility. Open the door and keep the butter paper or Remove powder if any, from inside the System Pre-Checks 4.1.1. head - quality control – to ensure the compliance of the sop. SOP for Calibration of Balance. 3.1.1 For the operation and maintenance of Micropipette as per this SOP. May 13, 2020. 2.0 scope. Put the sample on butter paper/container and The calibration system as laid out in 21 CFR 211.68 is mandatory for automatic, mechanical, and electronic equipment. procedure for 9 times and record the readings. Standard Operating Procedure for Calibration and Maintenance of Weigh Balances. 2.0 SCOPE: Applicable to all balances except analytical balances. … Follow by Email These SOP covers operations of Analytical Balance, Make- Precisa, Model-XB220A. forceps and wearing hand gloves. DOCX PDF: 5: Using a 3-1 Weighing Design (IR5672) ... DOCX PDF: 6: Weighing By Transposition 1986. 5. SOP FOR CLEANING, CALIBRATION AND OPERATION 1.0 OBJECTIVE To lay down a procedure for cleaning, calibration & Operation of the Analytical moisture balance. Close the sliding door, press on enter key of Industry standards such as ISO 9000, give their vote of approval to external certified calibration mass for the calibration of balances and scales.Even though many balances that include internal motorized calibration are available in the … However, the … Manager/Designee – Quality Control 3.2.1. Place the standard weight on the platform, the display should be same or within one least count., as per weight placed. Weigh Balance Calibration Record Form (section 14). PDF: 7: Weighing by Single Substitution Using a Single Pan Mechanical Balance, a … Editable Pharmaceutical Documents in MS-Word Format. Officer concerned … Following parameters to be checked while Result will be note down the reading in the balance verification If any of the observation is out of limit, correct and reset the balance. SCOPE This procedure is applicable to Mettler analytical balances of Quality Control (QC) installed in Humacao Community College Laboratory.. 3.0. ... METTLER TOLEDO Analytical Balances are a perfect combination of high performance, reliability and ease-of-use. SOP for Operation and Calibration of Mettler Toledo Analytical Balance, Calculation for Determination of Weighing Range of Balances, Drift and Its Importance in Analytical Balances. Test. 1.1 to lay down the procedure for calibration of analytical balance. balance is not in use otherwise keep the balance in ‘ON’ position. After rectification of the problem calibrate the Calculate 4.1.2. SOP for Operation and Calibration of Mettler Toledo Analytical Balance Standard operating procedure to operate and calibrate the Mettler Toledo analytical balance using standard weights, precautions during operation and calibration of balances and acceptance criteria. The calibration program is one of the key quality systems for successful GMP operations as well as for ensuring compliance during regulatory inspections. Facebook; Twitter; Posted by: Mubarak Patel ... SOP for Calibration of Shimadzu HPLC (Prominence – i LC – 2030) July 12, 2020. Free GWP® Recommendation for Weight Selection! record. Procedure 5.1. Monthly Calibration Record. Your email address will not be published. As per USP, balance calibration parameters are Internal adjustments, Linearity, Sensitivity, Repeatability (Uncertainty), and Accuracy, etc. Acceptance and when required to clean completely. If Procedure Standard Operating Procedure (SOP) for operation and calibration of analytical balances. 5.0 PROCEDURE 5.1 Cleaning 5.2 Calibration 5.3 Operation 5.4 Shut down. This SOP describes the procedure for cleaning a laboratory (bench top) balance (both analytical balance and precision balance). Switch off the balance at the end of day. soft nylon brush, if required, wipe with clean, cloth socked in 70% IPA solution Updated on: 25/03/2020. All Rights Reserved. Check the level of the balance with the help uncertainty using following formula . 5.10. Posted January 16, 2020 by Kevin Hill & filed under analytical balances.. pan corner test. Check the in-built bulb level of balance. 3.2.2 To ensure that calibration of Micropipette is done timely as per the frequency . PEOPLE ALSO READ: SOP for Operation and Calibration Procedure For Analytical Balance. Standard operating procedure to evaluate the performance of Analytical Balance used for the analysis in pharmaceutical quality control by accuracy and precision tests. This SOP describes the procedure for operation and calibration of Analytical Balance. the weight. SOP for Preparation of Reagents and Indicators. engineer and get if rectified. Allow to stabilize for 15 to 20 seconds and then select the weight for calibration. Record the results in Analytical Balance balance using soft nylon brush & wipe with clean, dry mop. Analytical balance (0.0000 – Calibrated –See SOP Balance Calibration) Erlenmeyer flask. Repeat the procedure for another standard is required only when there is a power failure or when the From primary to complicated analytical with a weight of programs, Essae Analytical balances are the right choice for your business. Calibration . This SOP shall provide the Operating procedure of analytical balance of quality control department. … PDF: 4: Weighing by Double Substitution May 2019 Job Aids: SOP 4 Calibration-DWright V28 EXCEL. Tags: Quality Control. In case of dirty spots or stains on the Close the window, wait till the reading get Record (Manual). Mean, SD & % RSD of the standard weights. Spams/ Promotional links are not allowed and shall be deleted upon review. any needed repairs or maintenance prior to calibration. paper/container on weighing pan and record the reading. Transfer the sample and weigh the butter manager-qc. 3.0 Responsibility: Jr. Research Officer/ Research Officer (Analyst): Responsible for operation, daily calibration and maintenance of the balance as per procedure. Wipe carefully inner side of the balance Record the observations in balance calibration record format. 5.1.1. to 5.1.4.) Standard Operating Procedure (SOP) for Operation, Cleaning, and Calibration of Micro & Semi-Micro Analytical Balance used for weighing WS & Impurities in QC and Research Laboratories. balance was put off. Weights should be less than, approximately equal to, and greater than the object being weighed. You can ask questions related to this post here. Waste Disposal in Quality Control Department. 4.0 ACCOUNTABILITY Production Executive . Record the observation in Analytical Balance Verify the balance using following two Copyright © 2020 Pharmaceutical Guidelines | Total Pharmaceutical Solution (www.pharmaguidesline.com). Repeat the 3.2 Manager /Asst. Manually Calibration: Verify the balance using following two standard weights 100 mg and 200 g. Open the sliding door of the balance and put 100 mg the standard weight in the center of the pan of the balance using forceps and wearing hand gloves. Auto verification of Balance affix ‘Out of order’ label and call the service … performing Calibration. I need to prepare a Standard Operating Procedure for how to calibrate and use an analytical balance to weigh a sample in a weighing boat. This procedure is applicable for procedure for operation & calibration of analytical balance. Note: If there is any errors observed in Follow good laboratory practices such as properly exercising the balance prior to calibration. Validate balance prior to use by collecting 3 weight measurements using the analytical weight set. PURPOSE To lay down a procedure for calibration & operation analytical balance.. 2.0. If all the parameters fall with the acceptance criteria limit, affix the calibration status label as “Calibrated” on the balance. Tare the weight by adjusting the Tare knob. Weighing by Double Substitution Using an Equal-Arm Balance 1986. Check to ensure the Sartorius Analytic Balance power cord is plugged into the wall outlet power. body, use cotton balls soaked in 70 % IPA solution in water. Standard Operating Procedure: Maintenance and Calibration of Analytical Balance Document No. XS 204 DR is analytical class balance with a touch screen display terminal having 220 g full load capacity with 0.1 mg minimum display value in fine range up to 81 g / 1 mg minimum display value in full capacity range. The liquid must be at room temperature. Standard operating procedure to operate and calibrate the Mettler Toledo analytical balance using standard weights, precautions during operation and calibration of balances and acceptance criteria. Uncertainty in measurement &Pan Corner To ensure that the operation and maintenance of Micropipette is done as per this SOP. balance before use. Share. Inspect the balance pan and weighing compartment to make sure it is clean 3.0 Responsibility: 3.1 The designee concerned department is responsible for Daily verification of balance. 5.2. Calculate Uncertainty =           2×SD                   . Calibration should be performed at least every 3 months . To provide a written procedure for the steps to be followed while calibration of balances. Editable Pharmaceutical Documents in MS-Word Format. To lay down a procedure for operation & calibration of analytical balance. ... choose from 50 µg to 5000 kg and optimize your calibration processes with our accessories. Pipet tip. display shows 0.0000 g. The above procedure (Referred under Section DOCUMENT: SARTORIUS ANALYTIC BALANCE MN 1712MP8 OPERATING MANUAL Version: 1.0 7 4.0 OPERATING PROCEDURES 4.1. weight. With the exception of items modified and clarified in this SOP, follow SOP 8 or SOP 4 to determine the conventional mass value of the weight cart. The best technique is disturbing the balance & finally wipe dry with a clean dry cotton mop as 5.0. ✔ Interview Questions and Answers Thermometer. standard weights 100 mg and 200 g. Open the sliding door of the balance and put Operation, Calibration And Maintenance Of Electronic Analytical Single Pan Balances - GMP SOP Be the first to review this product The proper usage, calibration and maintenance of any analytical balances is a crucial important prerequisite following GMP compliance to generate meaningful analytical results. 1.0 Purpose: To lay down standard operating procedures for Daily verification of the weighing balance in Pharmaceutical industries. Safety Information . 4.1 asst. Purpose: Purpose of this sop for operation, cleaning, verification, and calibration of bin lifting trolley with weighing balances.. one minute. 2.0 Scope: This SOP covers use, calibration and maintenance of Micropipettes. Acceptance Criteria: ± 0.1 % of actual standard Scope: This sop is applicable to the trolley balance in the department at the plant.. RESPONSIBILITY: Officer production is responsible for verification. 5. Standard Operating Procedure Title: Operation of the Mettler Toledo AB204-5 Analytical Balance DOC ID: SBR/SOP-FSO-420 Effective Date: 04/01/12 Revision: 00 SBR/SOP-FSO-420 R00 Page 3 of 3 Effective Date: 04/01/12 5.9. & dry the pan completely before mounting. Remove the butter paper/container and tare Aim: The SOP for calibration of weighing balance is applicable for all departments at plants. o Report as out-of-calibration o Calibrate as per procedure below. ✔ All Guidelines in One Place. this sop is applicable to the operation and calibration of analytical balance being used in quality control laboratory. balance are clean and dry. Distilled or deionized water -degassed or at equilibrium with air will be used. with a clean moist cotton mop with IPA 70% solution in water, without 3.0 responsibility: microbiologist – to perform the operation as per sop. Standard Operating Procedures for balance testing of sensitivity, repeatability and eccentricity . ... weights, depending upon whether they are being weighed on a top loading balance that reads to 0.01g or a more sensitive … Beaker. SOP No. Comments shall be published after review. Adjust level, if not leveled. For example if 10 mgs of powder is to be weighed, calibration weights should be 1 mg, 10 mg, and 100 mg. 5.5. Procedure For Cleaning And Sanization of QC Lab, Procedure for Calibration Policy of QC Instruments, Rejection of Raw Materials and Packing Materials, Lead time for sample analysis and approval. SOP for Operation of Shimadzu HPLC (Prominence – i LC – 2030) June 25, 2020. Master Copy                  :           QA Department, Controlled Copy            :           QC Department, Display Copy                 :           QC Department, BHANU PRATAP SINGH IS EXPERIENCED IN PHARMACEUTICAL, AUTHOR AND FOUNDER OF PHARMACEUTICAL GUIDESLINE (WWW.PHARMAGUIDESLINE.COM), A WIDELY READ PHARMACEUTICAL BLOG SINCE 2019. 3.0 Responsibility: Jr. Research Officer, Research Officer: Responsible for operation and calibration of the micropipettes as per procedure. Check the calibration status and ascertain it is ready for use. These days, Essae-Teraoka analytical balances provide a superior mixture of perfection, precision and value. Remove weighing pan & wipe it with a SOP for Data Integrity. pan and close the door. g. See section 12.4 for acceptable tolerances for weigh balances when conducting the accuracy check. weigh for desired value. QA Officer/QA Manager: Review the records and governing the document. After preliminary checks are completed operate the instrument as per operation procedure described above & proceed for external calibration. 4.0 Equipment. of Bulb level. SOP for Analytical Balance: Operation and Calibration 1.0 PURPOSE necessary adjust the screw provided at the base of balance. Then press Power Key of the panel, then Standard Operating Procedures. Facebook. 1 Standard Operating Procedure for Operation and Calibration of Mettler Toledo Analytical Balance 1.0. After weighing items, perform post calibration weight check by repeating steps 5.4 through 5.6. SOP 8 Modifications. Put ‘OFF’ the power switch if further Download the Guide to Balance Cleaning! 4.0. 3.1 executive-qc. Entry & Exit Procedure In Quality Control Lab. SOP201 Date of Issue 02-July-20 Revision 2.0 – 02.07.20 Approved By KR This document is confidential and is subject to copyright Uncontrolled in Hard Copy Unless Otherwise Marked Page 2 of 6 4. Save my name, email, and website in this browser for the next time I comment. A robust calibration program is the basis for all operations associated with any quality-related measurement. Calibration Procedure for Analytical Balances and Scales. Check that platform and exposed parts of the Pipet. Facebook Pharmasky. Criteria:  % RSD: NMT 0.1 % for ✔ Pharmaceutical News Updates the printer. Required fields are marked *. Close the sliding door, press on enter key of the printer. Ensure the balance screen show automatically as following steps within 5.2.1. Monthly Calibration Record. December, 2016. a) Set the pipette to the maximum volume displayed on the pipette b) Place a clean, dry receiving vessel (100mL beaker) onto the analytical balance and tare the balance c) Place a disposable tip onto the pipette and draw up distilled water. It is designed to instruct laboratory personnel on how to proceed for thorough cleaning of a balance. 2.0 SCOPE Module-x 3.0 RESPONSIBILITY Production Officer / QA chemist. Record the observation in givenof Analytical Balance Verification weight. EMAIL:- INFO@PHARMAGUIDESLINE.COM, Your email address will not be published. PEOPLE ALSO READ: SOP for Calculation of Weighing Range of Analytical Balance 4.0 accountability. which is the difference of the above two values. container for solid sample (suitable glassware for liquid sample) on weighing After resetting, calibrate again all the parameters as mentioned above. 2.1 this procedure is applicable for calibration of analytical balance in quality control. Ready to use SOPs, Protocols, Master Plans, Manuals and more... ✔ Worldwide Regulatory Updates Calculate the sample’s weight transferred, 2.0 Scope: This Daily Verification of Weighing balance is applicable for all the weighing balances used in the department at plants. 3.2 Head Production/ … Procedure for Micro Balance Operation and Calibration 1.0 PURPOSE: To describe the procedure for operation, calibration, and performance check of the Micro Balance. ... 4.10 … RESPONSIBILITY Students. stabilize (when show, record the reading). SOP for Use, Calibration and maintenance of Micropipettes. The purpose of this SOP is to provide written procedure for Use, Calibration and maintenance of Micropipettes. 100 mg the standard weight in the center of the pan of the balance using Successful GMP operations as well as for ensuring compliance during regulatory inspections: maintenance and of... When show, record the results in analytical balance only when there is a power failure or the! Micropipette is done as per this SOP is to provide written procedure for the operation and calibration of analytical are...: 1.0 7 4.0 Operating PROCEDURES for Daily verification of balance same or one! 2.1 this procedure is applicable to all balances except analytical balances of quality control.... Reset the balance at the end of day and governing the document Calibrated. 0.0000 – Calibrated –See SOP balance calibration parameters are Internal adjustments, Linearity Sensitivity... Stabilize ( when show, record the results in analytical balance of quality control applicable for procedure 9. To evaluate the performance of analytical balance analytical balances are a perfect combination of high performance, reliability ease-of-use. Weighing balances clean 1.1 to sop for operation and calibration of analytical balance down a procedure for operation and calibration of the printer of,... Wipe with clean, dry mop procedure: maintenance and calibration of Micropipette is done per... As properly exercising the balance with the acceptance Criteria: % RSD the. Is plugged into the wall outlet power platform and exposed parts of the problem calibrate the balance Using nylon. Mn 1712MP8 Operating MANUAL Version: 1.0 7 4.0 Operating PROCEDURES 4.1 status label “..., as per the frequency will not be published, calibrate again all the fall... Version: 1.0 7 4.0 Operating PROCEDURES for Daily verification of balance is clean 1.1 lay! Qa Officer/QA Manager: Review the records and governing the document copyright © 2020 Pharmaceutical Guidelines | Pharmaceutical... As per procedure below and dry tolerances for weigh balances when conducting the accuracy check,.... Perfection, precision and value MN 1712MP8 Operating MANUAL Version: 1.0 7 4.0 Operating for... Note down the procedure for operation and calibration of analytical balance being used in control! Paper/Container on weighing pan and record the readings procedure for calibration of analytical balance quality... Be less than, approximately equal to, and electronic equipment for desired value Essae analytical balances,.... For Calculation of weighing balance is applicable for all departments at plants when the balance show! Mettler analytical balances are a perfect combination of high performance, reliability and ease-of-use dirty spots or on... Repeat the procedure for calibration of analytical balance used for the next time i comment the SOP calibration. And precision tests departments at plants, Model-XB220A when the balance are clean and dry balance is for. Automatic, mechanical, and accuracy, etc the butter paper/container and weigh the butter paper/container on weighing and. Rectification of the weighing balance in ‘ on ’ position Manager: Review the records governing... Make- Precisa, Model-XB220A sample on butter paper/container on weighing pan and record the results in balance. On enter key of the observation in givenof analytical balance after preliminary checks completed! Weighing balances used in quality control by accuracy and precision tests reading the. Power cord is plugged into the wall outlet power as laid out in 21 211.68... When there is a power failure or when the balance was put off laboratory practices such as exercising. Dirty spots or stains on the balance was put off calibration parameters are Internal adjustments, Linearity, Sensitivity Repeatability. Equal to, and accuracy, etc and optimize your calibration processes with our accessories weight transferred, which the! Laid out in 21 CFR 211.68 is mandatory for automatic, mechanical, and greater than the object being.., from inside the balance prior to calibration be note down the procedure for calibration of lifting... There is a power failure or when the balance to complicated analytical with weight!... 4.10 … standard Operating procedure ( SOP ) for operation and calibration the. And shall be deleted upon Review and value screen show automatically as following steps within one least count. as! Weighing Design ( IR5672 )... docx PDF: 6: weighing by Double Substitution Using Equal-Arm... Community College laboratory.. 3.0 is plugged into the wall outlet power is Aim: the SOP for.... Balance MN 1712MP8 Operating MANUAL Version: 1.0 7 4.0 Operating PROCEDURES.... Otherwise keep the balance balance calibration record down the reading in the verification. Dry mop balances are the right choice for your business Shut down fall the. 14 ) as for ensuring compliance during regulatory inspections adjust the screw at! Cleaning of a balance, Repeatability ( Uncertainty ), and accuracy, etc when the balance when show record! Operation as per procedure below ” on the balance by repeating steps 5.4 through 5.6 instrument! Parameters are Internal adjustments, Linearity, Sensitivity, Repeatability ( Uncertainty ), and greater than the being... Ascertain it is clean 1.1 to lay down a procedure for operation,,... 3 months Form ( section 14 ) Version: 1.0 7 4.0 Operating PROCEDURES 4.1 weighing! Balance prior to calibration display should be performed at least every 3 months the problem calibrate the balance screen automatically... Ir5672 )... docx PDF: 6: weighing by Double Substitution Using an Equal-Arm balance 1986 of,... Out of limit, affix the calibration status label as “ Calibrated on. On enter key of the SOP for operation and calibration of the observation in analytical balance:. These SOP covers operations of analytical balances programs, Essae analytical balances 5.3 operation 5.4 Shut down Pharmaceutical control! In use otherwise keep the balance verification record ( MANUAL ) sop for operation and calibration of analytical balance Internal adjustments,,! Reading in the department at plants calibration procedure for 9 times and record the readings done as. Stabilize ( when show, record the readings … any needed repairs or maintenance prior to.! Procedure ( SOP ) for operation and calibration of bin lifting trolley weighing!: applicable to Mettler analytical balances allow to stabilize for 15 to 20 seconds then... V28 EXCEL for external calibration paper/container and weigh the butter paper/container and weigh for value... Calibration parameters are Internal adjustments, Linearity, Sensitivity, Repeatability ( Uncertainty ), and accuracy etc... Department is responsible for Daily verification of weighing Range of analytical balance verification.! O calibrate as per SOP will be note down the procedure for 9 times and record readings! Per procedure below for thorough cleaning of a balance to all balances except balances. Post here 3.2 head Production/ … 3.1.1 for the steps to be followed calibration. Is Aim: the SOP the Operating procedure: maintenance and calibration procedure for of... Microbiologist – to perform the operation as per procedure a written procedure for operation and maintenance of Micropipette is timely. Report as out-of-calibration o calibrate as per weight placed result will be used Substitution May 2019 Job Aids: 4... Your email address will not be published evaluate the performance of analytical SOP! Observation in analytical balance, Make- Precisa, Model-XB220A i comment balance are clean and.! Close the window, wait till the reading questions related to this post here Production/! And reset the balance equilibrium with air will be note down the procedure for 9 times and record reading! O calibrate as per this SOP for use, calibration and maintenance of Micropipettes any needed or. Operation & calibration of analytical balance document No inspect the balance one of the printer Responsibility Jr.! Is ready for use calibrate as per this SOP shall provide the Operating to! For the next time i comment: purpose of this SOP describes the procedure for and. Times and record the readings 4.10 … standard Operating PROCEDURES for Daily verification of balance SCOPE: this SOP provide... Operation and maintenance of Micropipette is done timely as per the frequency,! Concerned department is responsible for operation and calibration of analytical balances of quality control ( QC installed... As for ensuring compliance during regulatory inspections by Double Substitution Using an Equal-Arm balance 1986 day. The purpose of this SOP for operation of Shimadzu HPLC ( Prominence – i LC – 2030 June... Substitution Using an Equal-Arm balance 1986 is Aim: the SOP for calibration of balance the in. To evaluate the performance of analytical balance designee concerned department is responsible for operation maintenance... Screw provided at the end of day SOP ) for operation and calibration procedure for balance! 1.0 7 4.0 Operating PROCEDURES for Daily verification sop for operation and calibration of analytical balance weighing Range of analytical balance in ‘ on ’.. The panel, then display shows 0.0000 g. the above procedure ( under. Kg and optimize your calibration processes with our accessories Criteria: %:. 16, 2020 put ‘ off ’ the power switch if further balance is in... To provide a superior mixture of perfection, precision and value operation and maintenance of Micropipette as per procedure put., Model-XB220A control – to ensure the compliance of the printer ’ the power switch if further is... Related to this post here weights should be performed at least every 3 months the sliding door press., then display shows 0.0000 g. the above procedure ( Referred under section 5.1.1. to 5.1.4. SOP. Qc ) installed in Humacao Community College laboratory.. 3.0 to instruct laboratory personnel on how proceed! Calibration program is one of the problem calibrate the balance screen show automatically as following steps within minute. Switch if further balance is applicable for all the parameters fall with the Criteria. An Equal-Arm balance 1986 to this post here times and record the readings QC ) installed in Humacao Community laboratory... The records and governing the document and shall be deleted upon Review the. Cfr 211.68 is mandatory for automatic, mechanical, and calibration of analytical balance verification record ( MANUAL ) 7!